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Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality
BACKGROUND: Many patients with symptomatic severe aortic stenosis do not undergo aortic valve replacement (AVR) despite clinical guidelines. This study analyzed the association of managing provider type with cardiac specialist follow‐up, AVR, and mortality for patients with newly diagnosed severe ao...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333396/ https://www.ncbi.nlm.nih.gov/pubmed/35766279 http://dx.doi.org/10.1161/JAHA.121.025164 |
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author | Pellikka, Patricia A. Padang, Ratnasari Scott, Christopher G. Murphy, Shannon M. E. Fabunmi, Rosalind Thaden, Jeremy J. |
author_facet | Pellikka, Patricia A. Padang, Ratnasari Scott, Christopher G. Murphy, Shannon M. E. Fabunmi, Rosalind Thaden, Jeremy J. |
author_sort | Pellikka, Patricia A. |
collection | PubMed |
description | BACKGROUND: Many patients with symptomatic severe aortic stenosis do not undergo aortic valve replacement (AVR) despite clinical guidelines. This study analyzed the association of managing provider type with cardiac specialist follow‐up, AVR, and mortality for patients with newly diagnosed severe aortic stenosis (sAS). METHODS AND RESULTS: We identified adults with newly diagnosed sAS per echocardiography performed between January 2017 and March 2019 using Optum electronic health record data. We then selected from those meeting all eligibility criteria patients managed by a primary care provider (n=1707 [25%]) or cardiac specialist (n=5039 [75%]). We evaluated the association of managing provider type with cardiac specialist follow‐up, AVR, and mortality, as well as the independent association of cardiac specialist follow‐up and AVR with mortality, within 1 year of echocardiography detecting sAS. A subgroup analysis was limited to patients with symptomatic sAS. Patient characteristics and comorbidities at baseline were used for covariate‐adjusted cause‐specific and multivariable Cox proportional hazard models assessing group differences in outcomes by managing provider type. An adjusted Cox proportional hazard model with additional time‐dependent covariates for follow‐up and AVR was used to assess these practices' association with mortality. Within 1 year of echocardiography detecting sAS, data revealed that primary care provider management was associated with lower rates of cardiac specialist follow‐up (hazard ratio [HR], 0.47 [95% CI, 0.43–0.50], P<0.0001) and AVR (HR, 0.58 [95% CI, 0.53–0.64], P<0.0001) and with higher 1‐year mortality (HR, 1.45 [95% CI, 1.26–1.66], P<0.0001). Cardiac specialist follow‐up and AVR were independently associated with lower mortality (follow‐up: HR, 0.55 [95% CI, 0.48–0.63], P<0.0001; AVR: HR, 0.70 [95% CI, 0.60–0.83], P<0.0001). Results were similar for patients with symptomatic sAS. All analyses were adjusted for baseline patient characteristics and comorbidities. CONCLUSIONS: For patients newly diagnosed with sAS, we observed differences in rates of cardiac specialist follow‐up and AVR and risk of mortality between primary care provider‐ versus cardiologist‐managed patients with sAS. In addition, a lower likelihood of receiving follow‐up and AVR was independently associated with higher mortality. |
format | Online Article Text |
id | pubmed-9333396 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-93333962022-07-30 Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality Pellikka, Patricia A. Padang, Ratnasari Scott, Christopher G. Murphy, Shannon M. E. Fabunmi, Rosalind Thaden, Jeremy J. J Am Heart Assoc Original Research BACKGROUND: Many patients with symptomatic severe aortic stenosis do not undergo aortic valve replacement (AVR) despite clinical guidelines. This study analyzed the association of managing provider type with cardiac specialist follow‐up, AVR, and mortality for patients with newly diagnosed severe aortic stenosis (sAS). METHODS AND RESULTS: We identified adults with newly diagnosed sAS per echocardiography performed between January 2017 and March 2019 using Optum electronic health record data. We then selected from those meeting all eligibility criteria patients managed by a primary care provider (n=1707 [25%]) or cardiac specialist (n=5039 [75%]). We evaluated the association of managing provider type with cardiac specialist follow‐up, AVR, and mortality, as well as the independent association of cardiac specialist follow‐up and AVR with mortality, within 1 year of echocardiography detecting sAS. A subgroup analysis was limited to patients with symptomatic sAS. Patient characteristics and comorbidities at baseline were used for covariate‐adjusted cause‐specific and multivariable Cox proportional hazard models assessing group differences in outcomes by managing provider type. An adjusted Cox proportional hazard model with additional time‐dependent covariates for follow‐up and AVR was used to assess these practices' association with mortality. Within 1 year of echocardiography detecting sAS, data revealed that primary care provider management was associated with lower rates of cardiac specialist follow‐up (hazard ratio [HR], 0.47 [95% CI, 0.43–0.50], P<0.0001) and AVR (HR, 0.58 [95% CI, 0.53–0.64], P<0.0001) and with higher 1‐year mortality (HR, 1.45 [95% CI, 1.26–1.66], P<0.0001). Cardiac specialist follow‐up and AVR were independently associated with lower mortality (follow‐up: HR, 0.55 [95% CI, 0.48–0.63], P<0.0001; AVR: HR, 0.70 [95% CI, 0.60–0.83], P<0.0001). Results were similar for patients with symptomatic sAS. All analyses were adjusted for baseline patient characteristics and comorbidities. CONCLUSIONS: For patients newly diagnosed with sAS, we observed differences in rates of cardiac specialist follow‐up and AVR and risk of mortality between primary care provider‐ versus cardiologist‐managed patients with sAS. In addition, a lower likelihood of receiving follow‐up and AVR was independently associated with higher mortality. John Wiley and Sons Inc. 2022-06-29 /pmc/articles/PMC9333396/ /pubmed/35766279 http://dx.doi.org/10.1161/JAHA.121.025164 Text en © 2022 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Research Pellikka, Patricia A. Padang, Ratnasari Scott, Christopher G. Murphy, Shannon M. E. Fabunmi, Rosalind Thaden, Jeremy J. Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality |
title | Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality |
title_full | Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality |
title_fullStr | Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality |
title_full_unstemmed | Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality |
title_short | Impact of Managing Provider Type on Severe Aortic Stenosis Management and Mortality |
title_sort | impact of managing provider type on severe aortic stenosis management and mortality |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333396/ https://www.ncbi.nlm.nih.gov/pubmed/35766279 http://dx.doi.org/10.1161/JAHA.121.025164 |
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