Optimal dosing of cefotaxime and desacetylcefotaxime for critically ill paediatric patients. Can we use microsampling?

OBJECTIVES: To describe the population pharmacokinetics of cefotaxime and desacetylcefotaxime in critically ill paediatric patients and provide dosing recommendations. We also sought to evaluate the use of capillary microsampling to facilitate data-rich blood sampling. METHODS: Patients were recruit...

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Detalles Bibliográficos
Autores principales: Guerra Valero, Yarmarly C, Dorofaeff, Tavey, Coulthard, Mark G, Sparkes, Louise, Lipman, Jeffrey, Wallis, Steven C, Roberts, Jason A, Parker, Suzanne L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333413/
https://www.ncbi.nlm.nih.gov/pubmed/35678266
http://dx.doi.org/10.1093/jac/dkac168

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