Single-cell network biology characterizes cell type gene regulation for drug repurposing and phenotype prediction in Alzheimer’s disease

Dysregulation of gene expression in Alzheimer’s disease (AD) remains elusive, especially at the cell type level. Gene regulatory network, a key molecular mechanism linking transcription factors (TFs) and regulatory elements to govern gene expression, can change across cell types in the human brain a...

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Detalles Bibliográficos
Autores principales: Gupta, Chirag, Xu, Jielin, Jin, Ting, Khullar, Saniya, Liu, Xiaoyu, Alatkar, Sayali, Cheng, Feixiong, Wang, Daifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333448/
https://www.ncbi.nlm.nih.gov/pubmed/35849618
http://dx.doi.org/10.1371/journal.pcbi.1010287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333448/
https://www.ncbi.nlm.nih.gov/pubmed/35849618
http://dx.doi.org/10.1371/journal.pcbi.1010287

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