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Sample-efficient identification of high-dimensional antibiotic synergy with a normalized diagonal sampling design

Antibiotic resistance is an important public health problem. One potential solution is the development of synergistic antibiotic combinations, in which the combination is more effective than the component drugs. However, experimental progress in this direction is severely limited by the number of sa...

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Detalles Bibliográficos
Autores principales: Brennan, Jennifer, Jain, Lalit, Garman, Sofia, Donnelly, Ann E., Wright, Erik Scott, Jamieson, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333450/
https://www.ncbi.nlm.nih.gov/pubmed/35849634
http://dx.doi.org/10.1371/journal.pcbi.1010311