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2-Deoxy-D-glucose and combined 2-Deoxy-D-glucose/albendazole exhibit therapeutic efficacy against Echinococcus granulosus protoscoleces and experimental alveolar echinococcosis

2-Deoxy-D-glucose (2-DG) is a glucose analog used as a promising anticancer agent. It exerts its effects by inhibiting the glycolytic energy metabolism to deplete cells of energy. The larval stage of Echinococcus relies on glycolysis for energy production. Therefore, in this study, we investigated t...

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Detalles Bibliográficos
Autores principales: Xin, Qi, Lv, Wei, Xu, Yunxi, Luo, Yumei, Zhao, Caifang, Wang, Bichen, Yuan, Miaomiao, Li, Huanping, Song, Xiaoxia, Jing, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333451/
https://www.ncbi.nlm.nih.gov/pubmed/35849619
http://dx.doi.org/10.1371/journal.pntd.0010618

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