Examination of the Cell Cycle Dependence of Cytosine and Adenine Base Editors

Base editors (BEs) are genome editing agents that install point mutations with high efficiency and specificity. Due to their reliance on uracil and inosine DNA damage intermediates (rather than double-strand DNA breaks, or DSBs), it has been hypothesized that BEs rely on more ubiquitous DNA repair p...

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Detalles Bibliográficos
Autores principales: Burnett, Cameron A., Wong, Ashley T., Vasquez, Carlos A., McHugh, Colleen A., Yeo, Gene W., Komor, Alexis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genome Editing
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333457/
https://www.ncbi.nlm.nih.gov/pubmed/35910415
http://dx.doi.org/10.3389/fgeed.2022.923718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9333457/
https://www.ncbi.nlm.nih.gov/pubmed/35910415
http://dx.doi.org/10.3389/fgeed.2022.923718

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