Cargando…

IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning

A genetic disorder is a serious disease that affects a large number of individuals around the world. There are various types of genetic illnesses, however, we focus on mitochondrial and multifactorial genetic disorders for prediction. Genetic illness is caused by a number of factors, including a def...

Descripción completa

Detalles Bibliográficos
Autores principales: Rahman, Atta-ur, Nasir, Muhammad Umar, Gollapalli, Mohammed, Alsaif, Suleiman Ali, Almadhor, Ahmad S., Mehmood, Shahid, Khan, Muhammad Adnan, Mosavi, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334098/
https://www.ncbi.nlm.nih.gov/pubmed/35909844
http://dx.doi.org/10.1155/2022/2650742
_version_ 1784759026213453824
author Rahman, Atta-ur
Nasir, Muhammad Umar
Gollapalli, Mohammed
Alsaif, Suleiman Ali
Almadhor, Ahmad S.
Mehmood, Shahid
Khan, Muhammad Adnan
Mosavi, Amir
author_facet Rahman, Atta-ur
Nasir, Muhammad Umar
Gollapalli, Mohammed
Alsaif, Suleiman Ali
Almadhor, Ahmad S.
Mehmood, Shahid
Khan, Muhammad Adnan
Mosavi, Amir
author_sort Rahman, Atta-ur
collection PubMed
description A genetic disorder is a serious disease that affects a large number of individuals around the world. There are various types of genetic illnesses, however, we focus on mitochondrial and multifactorial genetic disorders for prediction. Genetic illness is caused by a number of factors, including a defective maternal or paternal gene, excessive abortions, a lack of blood cells, and low white blood cell count. For premature or teenage life development, early detection of genetic diseases is crucial. Although it is difficult to forecast genetic disorders ahead of time, this prediction is very critical since a person's life progress depends on it. Machine learning algorithms are used to diagnose genetic disorders with high accuracy utilizing datasets collected and constructed from a large number of patient medical reports. A lot of studies have been conducted recently employing genome sequencing for illness detection, but fewer studies have been presented using patient medical history. The accuracy of existing studies that use a patient's history is restricted. The internet of medical things (IoMT) based proposed model for genetic disease prediction in this article uses two separate machine learning algorithms: support vector machine (SVM) and K-Nearest Neighbor (KNN). Experimental results show that SVM has outperformed the KNN and existing prediction methods in terms of accuracy. SVM achieved an accuracy of 94.99% and 86.6% for training and testing, respectively.
format Online
Article
Text
id pubmed-9334098
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-93340982022-07-29 IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning Rahman, Atta-ur Nasir, Muhammad Umar Gollapalli, Mohammed Alsaif, Suleiman Ali Almadhor, Ahmad S. Mehmood, Shahid Khan, Muhammad Adnan Mosavi, Amir Comput Intell Neurosci Research Article A genetic disorder is a serious disease that affects a large number of individuals around the world. There are various types of genetic illnesses, however, we focus on mitochondrial and multifactorial genetic disorders for prediction. Genetic illness is caused by a number of factors, including a defective maternal or paternal gene, excessive abortions, a lack of blood cells, and low white blood cell count. For premature or teenage life development, early detection of genetic diseases is crucial. Although it is difficult to forecast genetic disorders ahead of time, this prediction is very critical since a person's life progress depends on it. Machine learning algorithms are used to diagnose genetic disorders with high accuracy utilizing datasets collected and constructed from a large number of patient medical reports. A lot of studies have been conducted recently employing genome sequencing for illness detection, but fewer studies have been presented using patient medical history. The accuracy of existing studies that use a patient's history is restricted. The internet of medical things (IoMT) based proposed model for genetic disease prediction in this article uses two separate machine learning algorithms: support vector machine (SVM) and K-Nearest Neighbor (KNN). Experimental results show that SVM has outperformed the KNN and existing prediction methods in terms of accuracy. SVM achieved an accuracy of 94.99% and 86.6% for training and testing, respectively. Hindawi 2022-07-21 /pmc/articles/PMC9334098/ /pubmed/35909844 http://dx.doi.org/10.1155/2022/2650742 Text en Copyright © 2022 Atta-ur Rahman et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rahman, Atta-ur
Nasir, Muhammad Umar
Gollapalli, Mohammed
Alsaif, Suleiman Ali
Almadhor, Ahmad S.
Mehmood, Shahid
Khan, Muhammad Adnan
Mosavi, Amir
IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning
title IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning
title_full IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning
title_fullStr IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning
title_full_unstemmed IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning
title_short IoMT-Based Mitochondrial and Multifactorial Genetic Inheritance Disorder Prediction Using Machine Learning
title_sort iomt-based mitochondrial and multifactorial genetic inheritance disorder prediction using machine learning
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334098/
https://www.ncbi.nlm.nih.gov/pubmed/35909844
http://dx.doi.org/10.1155/2022/2650742
work_keys_str_mv AT rahmanattaur iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT nasirmuhammadumar iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT gollapallimohammed iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT alsaifsuleimanali iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT almadhorahmads iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT mehmoodshahid iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT khanmuhammadadnan iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning
AT mosaviamir iomtbasedmitochondrialandmultifactorialgeneticinheritancedisorderpredictionusingmachinelearning