Vasospastic Angina: An Immune-related Adverse Event

A 54-year-old Japanese woman was admitted to our ward because of recurrent chest pain at rest for 2 months. She had been treated with nivolumab, an immune checkpoint inhibitor for inoperable advanced hypopharyngeal cancer for 21 months. She had no chest pain after cessation of nivolumab treatment. C...

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Detalles Bibliográficos
Autores principales: Kumamoto, Taku, Kawano, Hiroaki, Kurobe, Masaya, Akashi, Ryohei, Yonekura, Tsuyoshi, Ikeda, Satoshi, Maemura, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334223/
https://www.ncbi.nlm.nih.gov/pubmed/34866103
http://dx.doi.org/10.2169/internalmedicine.8540-21
Descripción
Sumario:A 54-year-old Japanese woman was admitted to our ward because of recurrent chest pain at rest for 2 months. She had been treated with nivolumab, an immune checkpoint inhibitor for inoperable advanced hypopharyngeal cancer for 21 months. She had no chest pain after cessation of nivolumab treatment. Cardiac catheterization confirmed the presence of vasospastic angina. Benidipine 8 mg was started, and she had no chest pain even after resuming therapy with nivolumab. Vasospastic angina is an adverse effect of nivolumab.

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