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RGS6 suppresses TGF-β-induced epithelial–mesenchymal transition in non-small cell lung cancers via a novel mechanism dependent on its interaction with SMAD4

Regulator of G-protein signaling 6 (RGS6) is a newly discovered tumor suppressor that has been shown to be protective in development of various cancers such as breast cancer and bladder cancer. But the mechanisms underlying these tumor-suppressing functions of RGS6 are not fully understood. Here, we...

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Detalles Bibliográficos
Autores principales: Wang, Zhao, Chen, Jun, Wang, Shengjie, Sun, Zelong, Lei, Zhe, Zhang, Hong-Tao, Huang, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334288/
https://www.ncbi.nlm.nih.gov/pubmed/35902557
http://dx.doi.org/10.1038/s41419-022-05093-0