Micro-hydrogel injectables that deliver effective CAR-T immunotherapy against 3D solid tumor spheroids

Chimeric antigen receptor (CAR-) T cells are revolutionizing cancer treatment, as a direct result of their clinical impact on the treatment of hematological malignancies. However for solid tumors, CAR-T cell therapeutic efficacy remains limited, primarily due to the complex immunosuppressive tumor m...

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Detalles Bibliográficos
Autores principales: Suraiya, Anisha B., Evtimov, Vera J., Truong, Vinh X., Boyd, Richard L., Forsythe, John S., Boyd, Nicholas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334344/
https://www.ncbi.nlm.nih.gov/pubmed/35905640
http://dx.doi.org/10.1016/j.tranon.2022.101477

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