XAF1 drives apoptotic switch of endoplasmic reticulum stress response through destabilization of GRP78 and CHIP

X-linked inhibitor of apoptosis-associated factor-1 (XAF1) is a stress-inducible tumor suppressor that is commonly inactivated in many human cancers. Despite accumulating evidence for the pro-apoptotic role for XAF1 under various stressful conditions, its involvement in endoplasmic reticulum (ER) st...

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Detalles Bibliográficos
Autores principales: Lee, Kyung-Woo, Hong, Hui-Ra, Lim, Ji-Sun, Ko, Kyung-Phil, Lee, Min-Goo, Chi, Sung-Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334361/
https://www.ncbi.nlm.nih.gov/pubmed/35902580
http://dx.doi.org/10.1038/s41419-022-05112-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334361/
https://www.ncbi.nlm.nih.gov/pubmed/35902580
http://dx.doi.org/10.1038/s41419-022-05112-0

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