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Cardiomyocytes induced from hiPSCs by well-defined compounds have therapeutic potential in heart failure by secreting PDGF-BB

Recent studies have suggested that transplant of hiPS-CMs is a promising approach for treating heart failure. However, the optimally clinical benefits have been hampered by the immature nature of the hiPS-CMs, and the hiPS-CMs-secreted proteins contributing to the repair of cardiomyocytes remain lar...

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Detalles Bibliográficos
Autores principales: Li, Hongmei, Wu, Fenfang, Huang, Guangrui, Wu, Di, Wang, Ting, Wang, Xiashuang, Wang, Kai, Feng, Yuyin, Xu, Anlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334380/
https://www.ncbi.nlm.nih.gov/pubmed/35902567
http://dx.doi.org/10.1038/s41392-022-01045-4