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Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature

Left-side portal hypertension (LSPH) is caused by isolated obstruction of the splenic vein and is associated with esophagogastric varices that extend from the lower esophagus to the greater curvature of the gastric body. Here, we report on a 74-year-old man with a pancreatic neuroendocrine neoplasm...

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Autores principales: Matsui, Teppei, Nagai, Hidenari, Amanuma, Makoto, Kobayashi, Kojiro, Ogino, Yu, Mukozu, Takanori, Wakui, Noritaka, Okano, Naoki, Kikuchi, Yoshinori, Matsuda, Takahisa, Igarashi, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334412/
https://www.ncbi.nlm.nih.gov/pubmed/35430638
http://dx.doi.org/10.1007/s12328-022-01631-7
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author Matsui, Teppei
Nagai, Hidenari
Amanuma, Makoto
Kobayashi, Kojiro
Ogino, Yu
Mukozu, Takanori
Wakui, Noritaka
Okano, Naoki
Kikuchi, Yoshinori
Matsuda, Takahisa
Igarashi, Yoshinori
author_facet Matsui, Teppei
Nagai, Hidenari
Amanuma, Makoto
Kobayashi, Kojiro
Ogino, Yu
Mukozu, Takanori
Wakui, Noritaka
Okano, Naoki
Kikuchi, Yoshinori
Matsuda, Takahisa
Igarashi, Yoshinori
author_sort Matsui, Teppei
collection PubMed
description Left-side portal hypertension (LSPH) is caused by isolated obstruction of the splenic vein and is associated with esophagogastric varices that extend from the lower esophagus to the greater curvature of the gastric body. Here, we report on a 74-year-old man with a pancreatic neuroendocrine neoplasm (NEN) in the pancreatic tail with multiple liver metastases. We decided that partial splenic embolization (PSE) was the best course of treatment to prevent rupture of the gastric varices, which were classified as markedly enlarged, nodular, or tumor-shaped and showed erosion of the mucosa. After PSE, the patient had no major complications and was discharged. At 3 and 6 months after the procedure, esophagogastroduodenoscopy and enhanced computerized tomography showed that the gastric varices had improved. This case demonstrates the usefulness of PSE for LSPH in patients with unresected pancreatic NEN.
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spelling pubmed-93344122022-07-30 Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature Matsui, Teppei Nagai, Hidenari Amanuma, Makoto Kobayashi, Kojiro Ogino, Yu Mukozu, Takanori Wakui, Noritaka Okano, Naoki Kikuchi, Yoshinori Matsuda, Takahisa Igarashi, Yoshinori Clin J Gastroenterol Case Report Left-side portal hypertension (LSPH) is caused by isolated obstruction of the splenic vein and is associated with esophagogastric varices that extend from the lower esophagus to the greater curvature of the gastric body. Here, we report on a 74-year-old man with a pancreatic neuroendocrine neoplasm (NEN) in the pancreatic tail with multiple liver metastases. We decided that partial splenic embolization (PSE) was the best course of treatment to prevent rupture of the gastric varices, which were classified as markedly enlarged, nodular, or tumor-shaped and showed erosion of the mucosa. After PSE, the patient had no major complications and was discharged. At 3 and 6 months after the procedure, esophagogastroduodenoscopy and enhanced computerized tomography showed that the gastric varices had improved. This case demonstrates the usefulness of PSE for LSPH in patients with unresected pancreatic NEN. Springer Nature Singapore 2022-04-16 2022 /pmc/articles/PMC9334412/ /pubmed/35430638 http://dx.doi.org/10.1007/s12328-022-01631-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Case Report
Matsui, Teppei
Nagai, Hidenari
Amanuma, Makoto
Kobayashi, Kojiro
Ogino, Yu
Mukozu, Takanori
Wakui, Noritaka
Okano, Naoki
Kikuchi, Yoshinori
Matsuda, Takahisa
Igarashi, Yoshinori
Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
title Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
title_full Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
title_fullStr Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
title_full_unstemmed Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
title_short Usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
title_sort usefulness of partial splenic embolization for left-sided portal hypertension in a patient with a pancreatic neuroendocrine neoplasm: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334412/
https://www.ncbi.nlm.nih.gov/pubmed/35430638
http://dx.doi.org/10.1007/s12328-022-01631-7
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