Induction of severe hypoxemia and low lung recruitability for the evaluation of therapeutic ventilation strategies: a translational model of combined surfactant-depletion and ventilator-induced lung injury

BACKGROUND: Models of hypoxemic lung injury caused by lavage-induced pulmonary surfactant depletion are prone to prompt recovery of blood oxygenation following recruitment maneuvers and have limited translational validity. We hypothesized that addition of injurious ventilation following surfactant-d...

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Detalles Bibliográficos
Autores principales: Boerger, Emilia, Russ, Martin, von Platen, Philip, Taher, Mahdi, Hinken, Lea, Pomprapa, Anake, Koebrich, Rainer, Konietschke, Frank, Graw, Jan Adriaan, Lachmann, Burkhard, Braun, Wolfgang, Leonhardt, Steffen, Pickerodt, Philipp A., Francis, Roland C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334469/
https://www.ncbi.nlm.nih.gov/pubmed/35902450
http://dx.doi.org/10.1186/s40635-022-00456-5

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