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Does Monitoring Total and Free Polymyxin B1 Plasma Concentrations Predict Polymyxin B-Induced Nephrotoxicity? A Retrospective Study in Critically Ill Patients

INTRODUCTION: The correlation between total and free polymyxin B (PMB including PMB1 and PMB2) exposure in vivo and acute kidney injury (AKI) remains obscure. This study explores the relationships between plasma exposure of PMB1 and PMB2 and nephrotoxicity, and investigates the risk factors for PMB-...

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Detalles Bibliográficos
Autores principales: Deng, Yang, Gu, Jun-Yuan, Li, Xin, Tong, Huan, Guo, Si-Wei, Xu, Bing, Li, You, Zhang, Bi-Kui, Li, Ying, Huang, Hai-Ying, Xiao, Gui-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334479/
https://www.ncbi.nlm.nih.gov/pubmed/35689791
http://dx.doi.org/10.1007/s40121-022-00655-3