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ISX-9 potentiates CaMKIIδ-mediated BMAL1 activation to enhance circadian amplitude
Circadian dysregulation associates with numerous diseases including metabolic dysfunction, sleep disorder, depression and aging. Given that declined circadian amplitude is a trait commonly found with compromised health, interventions that design in precluding circadian amplitude from dampening will...
Autores principales: | Li, Huilin, Ou, Jiali, Li, Yaqun, Xu, Niannian, Li, Qing, Wu, Ping, Peng, Chao, Tang, Yun-Chi, Chang, Hung-Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334596/ https://www.ncbi.nlm.nih.gov/pubmed/35902736 http://dx.doi.org/10.1038/s42003-022-03725-x |
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