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PAK6 promotes homologous-recombination to enhance chemoresistance to oxaliplatin through ATR/CHK1 signaling in gastric cancer
Chemoresistance remains the primary challenge of clinical treatment of gastric cancer (GC), making the biomarkers of chemoresistance crucial for treatment decision. Our previous study has reported that p21-actived kinase 6 (PAK6) is a prognostic factor for selecting which patients with GC are resist...
Autores principales: | Huang, Weicai, Han, Zhen, Sun, Zepang, Feng, Hao, Zhao, Liying, Yuan, Qingyu, Chen, Chuanli, Yu, Shitong, Hu, Yanfeng, Yu, Jiang, Liu, Hao, Li, Guoxin, Jiang, Yuming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334622/ https://www.ncbi.nlm.nih.gov/pubmed/35902562 http://dx.doi.org/10.1038/s41419-022-05118-8 |
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