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The role of cardiac computed tomography in predicting adverse coronary events

Cardiac computed tomography (CCT) is now considered a first-line diagnostic test for suspected coronary artery disease (CAD) providing a non-invasive, qualitative, and quantitative assessment of the coronary arteries and pericoronary regions. CCT assesses vascular calcification and coronary lumen na...

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Autores principales: Emfietzoglou, Maria, Mavrogiannis, Michail C., Samaras, Athanasios, Rampidis, Georgios P., Giannakoulas, George, Kampaktsis, Polydoros N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334665/
https://www.ncbi.nlm.nih.gov/pubmed/35911522
http://dx.doi.org/10.3389/fcvm.2022.920119
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author Emfietzoglou, Maria
Mavrogiannis, Michail C.
Samaras, Athanasios
Rampidis, Georgios P.
Giannakoulas, George
Kampaktsis, Polydoros N.
author_facet Emfietzoglou, Maria
Mavrogiannis, Michail C.
Samaras, Athanasios
Rampidis, Georgios P.
Giannakoulas, George
Kampaktsis, Polydoros N.
author_sort Emfietzoglou, Maria
collection PubMed
description Cardiac computed tomography (CCT) is now considered a first-line diagnostic test for suspected coronary artery disease (CAD) providing a non-invasive, qualitative, and quantitative assessment of the coronary arteries and pericoronary regions. CCT assesses vascular calcification and coronary lumen narrowing, measures total plaque burden, identifies plaque composition and high-risk plaque features and can even assist with hemodynamic evaluation of coronary lesions. Recent research focuses on computing coronary endothelial shear stress, a potent modulator in the development and progression of atherosclerosis, as well as differentiating an inflammatory from a non-inflammatory pericoronary artery environment using the simple measurement of pericoronary fat attenuation index. In the present review, we discuss the role of the above in the diagnosis of coronary atherosclerosis and the prediction of adverse cardiovascular events. Additionally, we review the current limitations of cardiac computed tomography as an imaging modality and highlight how rapid technological advancements can boost its capacity in predicting cardiovascular risk and guiding clinical decision-making.
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spelling pubmed-93346652022-07-30 The role of cardiac computed tomography in predicting adverse coronary events Emfietzoglou, Maria Mavrogiannis, Michail C. Samaras, Athanasios Rampidis, Georgios P. Giannakoulas, George Kampaktsis, Polydoros N. Front Cardiovasc Med Cardiovascular Medicine Cardiac computed tomography (CCT) is now considered a first-line diagnostic test for suspected coronary artery disease (CAD) providing a non-invasive, qualitative, and quantitative assessment of the coronary arteries and pericoronary regions. CCT assesses vascular calcification and coronary lumen narrowing, measures total plaque burden, identifies plaque composition and high-risk plaque features and can even assist with hemodynamic evaluation of coronary lesions. Recent research focuses on computing coronary endothelial shear stress, a potent modulator in the development and progression of atherosclerosis, as well as differentiating an inflammatory from a non-inflammatory pericoronary artery environment using the simple measurement of pericoronary fat attenuation index. In the present review, we discuss the role of the above in the diagnosis of coronary atherosclerosis and the prediction of adverse cardiovascular events. Additionally, we review the current limitations of cardiac computed tomography as an imaging modality and highlight how rapid technological advancements can boost its capacity in predicting cardiovascular risk and guiding clinical decision-making. Frontiers Media S.A. 2022-07-15 /pmc/articles/PMC9334665/ /pubmed/35911522 http://dx.doi.org/10.3389/fcvm.2022.920119 Text en Copyright © 2022 Emfietzoglou, Mavrogiannis, Samaras, Rampidis, Giannakoulas and Kampaktsis. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Emfietzoglou, Maria
Mavrogiannis, Michail C.
Samaras, Athanasios
Rampidis, Georgios P.
Giannakoulas, George
Kampaktsis, Polydoros N.
The role of cardiac computed tomography in predicting adverse coronary events
title The role of cardiac computed tomography in predicting adverse coronary events
title_full The role of cardiac computed tomography in predicting adverse coronary events
title_fullStr The role of cardiac computed tomography in predicting adverse coronary events
title_full_unstemmed The role of cardiac computed tomography in predicting adverse coronary events
title_short The role of cardiac computed tomography in predicting adverse coronary events
title_sort role of cardiac computed tomography in predicting adverse coronary events
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334665/
https://www.ncbi.nlm.nih.gov/pubmed/35911522
http://dx.doi.org/10.3389/fcvm.2022.920119
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