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Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women

Background The risks of adverse maternal and perinatal outcomes are not very clear in coronavirus disease 2019 (COVID-19)-positive pregnant women. Therefore, this study aimed to determine the maternal and fetal outcomes in COVID-19-positive pregnancies. Methodology This prospective, cohort study was...

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Autores principales: Shree, Pragya, Mittal, Nupur, Vishwakarma, Soniya, Verma, Vandana, Pandey, Virendra, Thadani, Ekta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334844/
https://www.ncbi.nlm.nih.gov/pubmed/35911372
http://dx.doi.org/10.7759/cureus.26411
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author Shree, Pragya
Mittal, Nupur
Vishwakarma, Soniya
Verma, Vandana
Pandey, Virendra
Thadani, Ekta
author_facet Shree, Pragya
Mittal, Nupur
Vishwakarma, Soniya
Verma, Vandana
Pandey, Virendra
Thadani, Ekta
author_sort Shree, Pragya
collection PubMed
description Background The risks of adverse maternal and perinatal outcomes are not very clear in coronavirus disease 2019 (COVID-19)-positive pregnant women. Therefore, this study aimed to determine the maternal and fetal outcomes in COVID-19-positive pregnancies. Methodology This prospective, cohort study was conducted in a tertiary care center over the period of one year. The study group comprised pregnant patients who presented with COVID-19 in the first and second waves of the pandemic. Maternal symptoms due to COVID-19 infection, comorbidities, number of admissions to the intensive care unit (ICU), and maternal mortality were noted for every patient. Perinatal outcomes were recorded in the form of intrauterine growth retardation (IUGR), mode of delivery, preterm deliveries, birth weight of newborns, neonatal intensive care unit (NICU) admissions, and neonatal mortality. Data analysis was done in the form of a variable percentage and mean ± standard deviation (SD). Results COVID-19-positive pregnant patients were mostly asymptomatic (48.07%). Term deliveries (37-40 weeks) were seen in 44 (89.8%) patients. The percentage of normal vaginal delivery was 74% and cesarean section was 24%. Out of 52 patients, two (3.8%) patients were admitted to the high dependency unit (HDU), one (1.9%) patient was admitted to the ICU, and 49 (94.3%) patients were in the isolation ward. Of the 49 live births, four (8.16%) newborns were admitted to the NICU. No neonatal death was recorded. Conclusions In this study, COVID-19-pregnant women were mostly asymptomatic. Neonates of COVID-19-infected women also mostly tested COVID-19 negative. More studies are needed with larger sample sizes to determine the effect of COVID-19 infection in pregnant women and neonates.
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spelling pubmed-93348442022-07-30 Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women Shree, Pragya Mittal, Nupur Vishwakarma, Soniya Verma, Vandana Pandey, Virendra Thadani, Ekta Cureus Emergency Medicine Background The risks of adverse maternal and perinatal outcomes are not very clear in coronavirus disease 2019 (COVID-19)-positive pregnant women. Therefore, this study aimed to determine the maternal and fetal outcomes in COVID-19-positive pregnancies. Methodology This prospective, cohort study was conducted in a tertiary care center over the period of one year. The study group comprised pregnant patients who presented with COVID-19 in the first and second waves of the pandemic. Maternal symptoms due to COVID-19 infection, comorbidities, number of admissions to the intensive care unit (ICU), and maternal mortality were noted for every patient. Perinatal outcomes were recorded in the form of intrauterine growth retardation (IUGR), mode of delivery, preterm deliveries, birth weight of newborns, neonatal intensive care unit (NICU) admissions, and neonatal mortality. Data analysis was done in the form of a variable percentage and mean ± standard deviation (SD). Results COVID-19-positive pregnant patients were mostly asymptomatic (48.07%). Term deliveries (37-40 weeks) were seen in 44 (89.8%) patients. The percentage of normal vaginal delivery was 74% and cesarean section was 24%. Out of 52 patients, two (3.8%) patients were admitted to the high dependency unit (HDU), one (1.9%) patient was admitted to the ICU, and 49 (94.3%) patients were in the isolation ward. Of the 49 live births, four (8.16%) newborns were admitted to the NICU. No neonatal death was recorded. Conclusions In this study, COVID-19-pregnant women were mostly asymptomatic. Neonates of COVID-19-infected women also mostly tested COVID-19 negative. More studies are needed with larger sample sizes to determine the effect of COVID-19 infection in pregnant women and neonates. Cureus 2022-06-28 /pmc/articles/PMC9334844/ /pubmed/35911372 http://dx.doi.org/10.7759/cureus.26411 Text en Copyright © 2022, Shree et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Emergency Medicine
Shree, Pragya
Mittal, Nupur
Vishwakarma, Soniya
Verma, Vandana
Pandey, Virendra
Thadani, Ekta
Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women
title Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women
title_full Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women
title_fullStr Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women
title_full_unstemmed Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women
title_short Maternal and Perinatal Outcomes of COVID-19-Positive Pregnant Women
title_sort maternal and perinatal outcomes of covid-19-positive pregnant women
topic Emergency Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334844/
https://www.ncbi.nlm.nih.gov/pubmed/35911372
http://dx.doi.org/10.7759/cureus.26411
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