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An Inducible Nitric Oxide Synthase Dimerization Inhibitor Prevents the Progression of Osteoarthritis

Objective: Osteoarthritis (OA) is a degenerative joint disease. Excessive nitric oxide (NO) mediates the chondrocyte inflammatory response, apoptosis, and extracellular matrix (ECM) degradation during the occurrence and development of OA. NO in chondrocytes is mainly produced by inducible nitric oxi...

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Detalles Bibliográficos
Autores principales: Xian Bo, Shang, Yan Jie, Wang, De Chao, Cai, Sai, Ma, Zhe, Wang, Ya Kun, Zhu, Hui Hui, Guo, Chen, Wang, Xiao, Ma, Zhong Yao, Hu, Hao Ran, Yu, Ji Sen, Zhang, Wen Dan, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334866/
https://www.ncbi.nlm.nih.gov/pubmed/35910349
http://dx.doi.org/10.3389/fphar.2022.861183