Toosendanin activates caspase-1 and induces maturation of IL-1β to inhibit type 2 porcine reproductive and respiratory syndrome virus replication via an IFI16-dependent pathway

Porcine reproductive and respiratory syndrome virus (PRRSV) is a prevalent and endemic swine pathogen which causes significant economic losses in the global swine industry. Multiple vaccines have been developed to prevent PRRSV infection. However, they provide limited protection. Moreover, no effect...

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Detalles Bibliográficos
Autores principales: Zhang, Mingxin, Lu, Chunni, Su, Lizhan, Long, Feixiang, Yang, Xia, Guo, Xiaofeng, Song, Gaopeng, An, Tongqing, Chen, Weisan, Chen, Jianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9334981/
https://www.ncbi.nlm.nih.gov/pubmed/35906635
http://dx.doi.org/10.1186/s13567-022-01077-2

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