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PDL1Binder: Identifying programmed cell death ligand 1 binding peptides by incorporating next-generation phage display data and different peptide descriptors
Monoclonal antibody drugs targeting the PD-1/PD-L1 pathway have showed efficacy in the treatment of cancer patients, however, they have many intrinsic limitations and inevitable drawbacks. Peptide inhibitors as alternatives might compensate for the drawbacks of current PD-1/PD-L1 interaction blocker...
Autores principales: | He, Bifang, Li, Bowen, Chen, Xue, Zhang, Qianyue, Lu, Chunying, Yang, Shanshan, Long, Jinjin, Ning, Lin, Chen, Heng, Huang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335124/ https://www.ncbi.nlm.nih.gov/pubmed/35910615 http://dx.doi.org/10.3389/fmicb.2022.928774 |
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