Cargando…
Female sexual behavior is disrupted in a preclinical mouse model of PCOS via an attenuated hypothalamic nitric oxide pathway
Women with polycystic ovary syndrome (PCOS) frequently experience decreased sexual arousal, desire, and sexual satisfaction. While the hypothalamus is known to regulate sexual behavior, the specific neuronal pathways affected in patients with PCOS are not known. To dissect the underlying neural circ...
Autores principales: | Silva, Mauro S. B., Decoster, Laurine, Trova, Sara, Mimouni, Nour E.H., Delli, Virginia, Chachlaki, Konstantina, Yu, Qiang, Boehm, Ulrich, Prevot, Vincent, Giacobini, Paolo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335209/ https://www.ncbi.nlm.nih.gov/pubmed/35867816 http://dx.doi.org/10.1073/pnas.2203503119 |
Ejemplares similares
-
OR17-06 Clinical And Mechanistic Insight For The Therapeutic Potential Of Intranasal Kisspeptin Administration To Treat Reproductive Disorders In Humans
por: Mills, Edouard G, et al.
Publicado: (2023) -
Overactivation of GnRH neurons is sufficient to trigger polycystic ovary syndrome-like traits in female mice
por: Silva, Mauro S.B., et al.
Publicado: (2023) -
Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism
por: Malone, Samuel Andrew, et al.
Publicado: (2019) -
Polycystic ovary syndrome mouse model by prenatal exposure to high anti-Müllerian hormone
por: Mimouni, Nour El Houda, et al.
Publicado: (2021) -
Changes in circulating forms of anti-Muüllerian hormone and androgens in women with and without PCOS: a systematic longitudinal study throughout pregnancy
por: Peigné, M, et al.
Publicado: (2023)