C-terminal glutamine acts as a C-degron targeted by E3 ubiquitin ligase TRIM7

The exposed N-terminal or C-terminal residues of proteins can act, in cognate sequence contexts, as degradation signals (degrons) that are targeted by specific E3 ubiquitin ligases for proteasome-dependent degradation by N-degron or C-degron pathways. Here, we discovered a distinct C-degron pathway,...

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Detalles Bibliográficos
Autores principales: Ru, Yawei, Yan, Xiaojie, Zhang, Bing, Song, Lili, Feng, Qiqi, Ye, Chen, Zhou, Zhili, Yang, Zhenzhen, Li, Yao, Zhang, Zhenjian, Li, Qianqian, Mi, Wenyi, Dong, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335266/
https://www.ncbi.nlm.nih.gov/pubmed/35867826
http://dx.doi.org/10.1073/pnas.2203218119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335266/
https://www.ncbi.nlm.nih.gov/pubmed/35867826
http://dx.doi.org/10.1073/pnas.2203218119

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