Cargando…

Toll-Like Receptor 4 Signaling in the Trabecular Meshwork

Primary open-angle glaucoma is one of the leading causes of blindness worldwide. With limited therapeutics targeting the pathogenesis at the trabecular meshwork (TM), there is a great need for identifying potential new targets. Recent evidence has implicated Toll-like receptor 4 (TLR4) and it is sig...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mzyk, Philip, Hernandez, Humberto, Le, Thanh, Ramirez, Jose Ricardo, McDowell, Colleen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335276/ https://www.ncbi.nlm.nih.gov/pubmed/35912101 http://dx.doi.org/10.3389/fcell.2022.936115

Ejemplares similares

A20 Attenuates the Fibrotic Response in the Trabecular Meshwork
por: Mzyk, Philip, et al.
Publicado: (2022)

Crosstalk Between Transforming Growth Factor Beta-2 and Toll-Like Receptor 4 in the Trabecular Meshwork
por: Hernandez, Humberto, et al.
Publicado: (2017)

A Role of Caveolae in Trabecular Meshwork Mechanosensing and Contractile Tone
por: De Ieso, Michael L., et al.
Publicado: (2022)

Integrin Crosstalk and Its Effect on the Biological Functions of the Trabecular Meshwork/Schlemm’s Canal
por: Faralli, Jennifer A., et al.
Publicado: (2022)

Cell senescence alters responses of porcine trabecular meshwork cells to shear stress
por: Du, Ruotian, et al.
Publicado: (2022)

Myocilin Gene Mutation Induced Autophagy Activation Causes Dysfunction of Trabecular Meshwork Cells
por: Yan, Xuejing, et al.
Publicado: (2022)

The Effects of Mechanical Stretch on Integrins and Filopodial-Associated Proteins in Normal and Glaucomatous Trabecular Meshwork Cells
por: Yang, Yong-Feng, et al.
Publicado: (2022)

BMP and Activin Membrane Bound Inhibitor Regulates the Extracellular Matrix in the Trabecular Meshwork
por: Hernandez, Humberto, et al.
Publicado: (2018)

Multiomics analysis reveals the mechanical stress-dependent changes in trabecular meshwork cytoskeletal-extracellular matrix interactions
por: Soundararajan, Avinash, et al.
Publicado: (2022)

Glucocorticoids Preferentially Influence Expression of Nucleoskeletal Actin Network and Cell Adhesive Proteins in Human Trabecular Meshwork Cells
por: Bachman, William, et al.
Publicado: (2022)

Extracellular Matrix Stiffness and TGFβ2 Regulate YAP/TAZ Activity in Human Trabecular Meshwork Cells
por: Li, Haiyan, et al.
Publicado: (2022)

ABCB1 transporter and Toll-like receptor 4 in trabecular meshwork cells
por: Grybauskas, Algis, et al.
Publicado: (2015)

Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals
por: Xu, Lijuan, et al.
Publicado: (2023)

Synergistic Effects of Toll-Like Receptor 1/2 and Toll-Like Receptor 3 Signaling Triggering Interleukin 27 Gene Expression in Chikungunya Virus-Infected Macrophages
por: Valdés-López, Juan Felipe, et al.
Publicado: (2022)

Toll Like Receptors as Sensors of the Tumor Microbial Dysbiosis: Implications in Cancer Progression
por: Le Noci, Valentino, et al.
Publicado: (2021)

Toll-Like Receptors as a Therapeutic Target in the Era of Immunotherapies
por: Farooq, Mariya, et al.
Publicado: (2021)

Toll-Like Receptors Signaling Pathway of Quercetin Regulating Avian Beta-Defensin in the Ileum of Broilers
por: Ying, Linlin, et al.
Publicado: (2022)

Eosinophil Activation by Toll-Like Receptor 4 Ligands Regulates Macrophage Polarization
por: Yoon, Jiyoung, et al.
Publicado: (2019)

Corrigendum: Eosinophil Activation by Toll-Like Receptor 4 Ligands Regulates Macrophage Polarization
por: Yoon, Jiyoung, et al.
Publicado: (2020)

The role of toll-like receptors in orchestrating osteogenic differentiation of mesenchymal stromal cells and osteoimmunology
por: Liu, Xiaoyang, et al.
Publicado: (2023)

Editorial: Toll-Like Receptors Throughout Life: From Controlling Physiological Processes to Determinants of Disease
por: Arnaboldi, Francesca, et al.
Publicado: (2022)

Depletion of Toll-Like Receptor-9 Attenuates Renal Tubulointerstitial Fibrosis After Ischemia-Reperfusion Injury
por: Zheng, Haofeng, et al.
Publicado: (2021)

Fibronectin extra domain A (FN-EDA) causes glaucomatous trabecular meshwork, retina, and optic nerve damage in mice
por: Mavlyutov, Timur A., et al.
Publicado: (2022)

Overexpression of Toll-Like Receptor 4 Affects Autophagy, Oxidative Stress, and Inflammatory Responses in Monocytes of Transgenic Sheep
por: Wang, Sutian, et al.
Publicado: (2020)

Toll-Like Receptor 4 as a Favorable Prognostic Marker in Bladder Cancer: A Multi-Omics Analysis
por: Lu, Jun-Lin, et al.
Publicado: (2021)

Toll-like Receptor 2 is Involved in Calcium Influx and Acrosome Reaction to Facilitate Sperm Penetration to Oocytes During in vitro Fertilization in Cattle
por: Ma, Dongxue, et al.
Publicado: (2022)

Differential Contribution of the Aryl-Hydrocarbon Receptor and Toll-Like Receptor Pathways to IL-8 Expression in Normal and Cystic Fibrosis Airway Epithelial Cells Exposed to Pseudomonas aeruginosa
por: Roussel, Lucie, et al.
Publicado: (2016)

Human Trabecular Meshwork Progenitors
por: Zhu, Qin, et al.
Publicado: (2019)

p38δ controls Mitogen- and Stress-activated Kinase-1 (MSK1) function in response to toll-like receptor activation in macrophages
por: Díaz-Mora, Ester, et al.
Publicado: (2023)

YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells
por: Peng, Jie, et al.
Publicado: (2018)

Impaired TRPV4-eNOS signaling in trabecular meshwork elevates intraocular pressure in glaucoma
por: Patel, Pinkal D., et al.
Publicado: (2021)

Gain-of-Function Mutations in the Toll-Like Receptor Pathway: TPL2-Mediated ERK1/ERK2 MAPK Activation, a Path to Tumorigenesis in Lymphoid Neoplasms?
por: Rousseau, Simon, et al.
Publicado: (2016)

Paying the Toll in Nuclear Reprogramming
por: Liu, Chun, et al.
Publicado: (2017)

Apoptosis in the trabecular meshwork of glaucomatous patients
por: Baleriola, Jimena, et al.
Publicado: (2008)

Two-photon imaging of the trabecular meshwork
por: Ammar, David A., et al.
Publicado: (2010)

Surgery on the Trabecular Meshwork: Histopathological Evidence
por: Bhartiya, Shibal, et al.
Publicado: (2015)

Oxidative stress and antioxidants in the trabecular meshwork
por: Wang, Mingxuan, et al.
Publicado: (2019)

Comparative Study of the Effects of Trabecular Meshwork Outflow Drugs on the Permeability and Nitric Oxide Production in Trabecular Meshwork Cells
por: Kim, Jae Woo
Publicado: (2017)

Priming With Toll-Like Receptor 3 Agonist Poly(I:C) Enhances Content of Innate Immune Defense Proteins but Not MicroRNAs in Human Mesenchymal Stem Cell-Derived Extracellular Vesicles
por: Pierce, Lisa M., et al.
Publicado: (2021)

The Senolytic Drug Navitoclax (ABT-263) Causes Trabecular Bone Loss and Impaired Osteoprogenitor Function in Aged Mice
por: Sharma, Anuj K., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ggl8h7qjpnj13v5romeurp8o2r