Mitochondrial genome undergoes de novo DNA methylation that protects mtDNA against oxidative damage during the peri-implantation window

Mitochondrial remodeling during the peri-implantation stage is the hallmark event essential for normal embryogenesis. Among the changes, enhanced oxidative phosphorylation is critical for supporting high energy demands of postimplantation embryos, but increases mitochondrial oxidative stress, which...

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Detalles Bibliográficos
Autores principales: Yue, Yuan, Ren, Likun, Zhang, Chao, Miao, Kai, Tan, Kun, Yang, Qianying, Hu, Yupei, Xi, Guangyin, Luo, Gang, Yang, Mingyao, Zhang, Jingyu, Hou, Zhuocheng, An, Lei, Tian, Jianhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335330/
https://www.ncbi.nlm.nih.gov/pubmed/35858425
http://dx.doi.org/10.1073/pnas.2201168119

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