Cargando…

Potential predictive value of comutant LRP1B and FAT for immune response in non-small cell lung cancer: LRP1B and FAT comutation enhance immune response

BACKGROUND: Preliminary investigation revealed that Low-density lipoprotein receptor-related protein 1b (LRP1B) and FAT atypical cadherin (FAT) family mutation might serve as immune regulators under certain tumor microenvironment. EXPERIMENTAL DESIGN: We curated a total of 70 non-small cell lung can...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hao, Fang, Ma, Qing, Zhong, Diansheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Neoplasia Press 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335390/ https://www.ncbi.nlm.nih.gov/pubmed/35905642 http://dx.doi.org/10.1016/j.tranon.2022.101493

Ejemplares similares

Comut-viz: efficiently creating and browsing comutation plots online
por: Duan, Qiaonan, et al.
Publicado: (2023)

CoMut: visualizing integrated molecular information with comutation plots
por: Crowdis, Jett, et al.
Publicado: (2020)

Comutations in DDR Pathways Predict Atezolizumab Response in Non-Small Cell Lung Cancer Patients
por: Xiong, Anning, et al.
Publicado: (2021)

APOBEC3 proteins can copackage and comutate HIV-1 genomes
por: Desimmie, Belete A., et al.
Publicado: (2016)

Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy
por: Qiu, Jiayue, et al.
Publicado: (2022)

Association of Tumor Protein p53 and Ataxia-Telangiectasia Mutated Comutation With Response to Immune Checkpoint Inhibitors and Mortality in Patients With Non–Small Cell Lung Cancer
por: Chen, Yu, et al.
Publicado: (2019)

Whole-exome sequencing identifies recurrent SF3B1 R625 mutation and comutation of NF1 and KIT in mucosal melanoma
por: Hintzsche, Jennifer D., et al.
Publicado: (2017)

Genetic features and clinical outcomes of patients with isolated and comutated DDX41-mutated myeloid neoplasms
por: Alkhateeb, Hassan B., et al.
Publicado: (2022)

KIF13B enhances the endocytosis of LRP1 by recruiting LRP1 to caveolae
por: Kanai, Yoshimitsu, et al.
Publicado: (2014)

Multi-faceted role of LRP1 in the immune system
por: Sizova, Olga, et al.
Publicado: (2023)

Clonal independence of JAK2 and CALR or MPL mutations in comutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing
por: Thompson, Ella R., et al.
Publicado: (2020)

sLRP1ng Up Glucose: LRP1 Regulates Hepatic Insulin Responses
por: Lee, Stephen D., et al.
Publicado: (2016)

Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy
por: Zhu, Mingyu, et al.
Publicado: (2022)

Aumolertinib in NSCLC with leptomeningeal involvement, harbouring concurrent EGFR exon 19 deletion and TP53 comutation: a case report
por: Qin, Zhiquan, et al.
Publicado: (2023)

LRP1 modulates the microglial immune response via regulation of JNK and NF-κB signaling pathways
por: Yang, Longyu, et al.
Publicado: (2016)

The impact of DNMT3A variant allele frequency and two different comutations on patients with de novo cytogenetically normal acute myeloid leukemia
por: Chen, Xian, et al.
Publicado: (2023)

The Mutation and Expression Level of LRP1B are Associated with Immune Infiltration and Prognosis in Hepatocellular Carcinoma
por: Wang, Mengmeng, et al.
Publicado: (2021)

Ectodomains of the LDL Receptor-Related Proteins LRP1b and LRP4 Have Anchorage Independent Functions In Vivo
por: Dietrich, Martin F., et al.
Publicado: (2010)

Low density lipoprotein receptors LRP-1 and LRP-2 in C. elegans
por: Minor, Paul J, et al.
Publicado: (2019)

LRP1B mutation is associated with tumor immune microenvironment and progression-free survival in lung adenocarcinoma treated with immune checkpoint inhibitors
por: He, Ziyi, et al.
Publicado: (2023)

LRP1B: A Giant Lost in Cancer Translation
por: Príncipe, Catarina, et al.
Publicado: (2021)

The association between LRP1 and chylomicron uptake after the ingestion of a high-fat meal
por: Frazier-Wood, AC, et al.
Publicado: (2012)

Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus
por: de Gonzalo-Calvo, David, et al.
Publicado: (2018)

Evaluate the Prognosis of MYC/TP53 Comutation in Chinese Patients with EGFR-Positive Advanced NSCLC Using Next-Generation Sequencing: A Retrospective Study
por: Cao, Jin, et al.
Publicado: (2022)

LRP5 and LRP6 in Wnt Signaling: Similarity and Divergence
por: Ren, Qian, et al.
Publicado: (2021)

LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types
por: Brown, Landon C, et al.
Publicado: (2021)

Association of LRP1B Mutation With Tumor Mutation Burden and Outcomes in Melanoma and Non-small Cell Lung Cancer Patients Treated With Immune Check-Point Blockades
por: Chen, Hao, et al.
Publicado: (2019)

Clinical efficacy of atezolizumab plus bevacizumab and chemotherapy in KRAS-mutated non-small cell lung cancer with STK11, KEAP1, or TP53 comutations: subgroup results from the phase III IMpower150 trial
por: West, Howard Jack, et al.
Publicado: (2022)

Corrigendum: Association of LRP1B Mutation With Tumor Mutation Burden and Outcomes in Melanoma and Non-small Cell Lung Cancer Patients Treated With Immune Check-Point Blockades
por: Chen, Hao, et al.
Publicado: (2019)

Publisher Correction: Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus
por: de Gonzalo-Calvo, David, et al.
Publicado: (2019)

Effects of LRP1B Regulated by HSF1 on Lipid Metabolism in Hepatocellular Carcinoma
por: Li, Miaomiao, et al.
Publicado: (2020)

Dissecting Molecular Differences between Wnt Coreceptors LRP5 and LRP6
por: MacDonald, Bryan T., et al.
Publicado: (2011)

Early response activation in repetition priming: an LRP study
por: Valt, Christian, et al.
Publicado: (2017)

LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease
por: Spuch, Carlos, et al.
Publicado: (2012)

LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis
por: Xian, Xunde, et al.
Publicado: (2017)

Where Wnts Went: The Exploding Field of Lrp5 and Lrp6 Signaling in Bone
por: Williams, Bart O, et al.
Publicado: (2009)

Correlation between LRP1B Mutations and Tumor Mutation Burden in Gastric Cancer
por: Hu, Sizhe, et al.
Publicado: (2021)

Development and validation of LRP1B mutation-associated prognostic model for hepatocellular carcinoma
por: Xu, Jian, et al.
Publicado: (2021)

Association between the LRP1B and APOE loci and the development of Parkinson’s disease dementia
por: Real, Raquel, et al.
Publicado: (2022)

Renal LRP2 expression in man and chicken is estrogen-responsive
por: Plieschnig, Julia A., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_2c1399sit5rkb6l4nfmdcvv9cp