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PTPRO knockdown protects against inflammation in hemorrhage shock-induced lung injury involving the NF-κB signaling pathway

BACKGROUND: Hemorrhage shock (HS) is characterized by decreased tissue oxygenation and organ damage due to severe blood loss. Protein tyrosine phosphatase receptor type O (PTPRO) is abnormally up-regulated in the rat lungs after trauma/HS. METHODS: To elucidate the regulatory mechanism of PTPRO in l...

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Detalles Bibliográficos
Autores principales: Huan, Zhirong, Tang, Ying, Xu, Ce, Cai, Jimin, Yao, Hao, Wang, Yan, Bu, Fanyu, Ge, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9335982/
https://www.ncbi.nlm.nih.gov/pubmed/35906634
http://dx.doi.org/10.1186/s12931-022-02118-2

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