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A biomedical event extraction method based on fine-grained and attention mechanism

BACKGROUND: Biomedical event extraction is a fundamental task in biomedical text mining, which provides inspiration for medicine research and disease prevention. Biomedical events include simple events and complex events. Existing biomedical event extraction methods usually deal with simple events a...

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Detalles Bibliográficos
Autores principales: He, Xinyu, Tai, Ping, Lu, Hongbin, Huang, Xin, Ren, Yonggong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336007/
https://www.ncbi.nlm.nih.gov/pubmed/35906547
http://dx.doi.org/10.1186/s12859-022-04854-0
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author He, Xinyu
Tai, Ping
Lu, Hongbin
Huang, Xin
Ren, Yonggong
author_facet He, Xinyu
Tai, Ping
Lu, Hongbin
Huang, Xin
Ren, Yonggong
author_sort He, Xinyu
collection PubMed
description BACKGROUND: Biomedical event extraction is a fundamental task in biomedical text mining, which provides inspiration for medicine research and disease prevention. Biomedical events include simple events and complex events. Existing biomedical event extraction methods usually deal with simple events and complex events uniformly, and the performance of complex event extraction is relatively low. RESULTS: In this paper, we propose a fine-grained Bidirectional Long Short Term Memory method for biomedical event extraction, which designs different argument detection models for simple and complex events respectively. In addition, multi-level attention is designed to improve the performance of complex event extraction, and sentence embeddings are integrated to obtain sentence level information which can resolve the ambiguities for some types of events. Our method achieves state-of-the-art performance on the commonly used dataset Multi-Level Event Extraction. CONCLUSIONS: The sentence embeddings enrich the global sentence-level information. The fine-grained argument detection model improves the performance of complex biomedical event extraction. Furthermore, the multi-level attention mechanism enhances the interactions among relevant arguments. The experimental results demonstrate the effectiveness of the proposed method for biomedical event extraction.
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spelling pubmed-93360072022-07-30 A biomedical event extraction method based on fine-grained and attention mechanism He, Xinyu Tai, Ping Lu, Hongbin Huang, Xin Ren, Yonggong BMC Bioinformatics Research BACKGROUND: Biomedical event extraction is a fundamental task in biomedical text mining, which provides inspiration for medicine research and disease prevention. Biomedical events include simple events and complex events. Existing biomedical event extraction methods usually deal with simple events and complex events uniformly, and the performance of complex event extraction is relatively low. RESULTS: In this paper, we propose a fine-grained Bidirectional Long Short Term Memory method for biomedical event extraction, which designs different argument detection models for simple and complex events respectively. In addition, multi-level attention is designed to improve the performance of complex event extraction, and sentence embeddings are integrated to obtain sentence level information which can resolve the ambiguities for some types of events. Our method achieves state-of-the-art performance on the commonly used dataset Multi-Level Event Extraction. CONCLUSIONS: The sentence embeddings enrich the global sentence-level information. The fine-grained argument detection model improves the performance of complex biomedical event extraction. Furthermore, the multi-level attention mechanism enhances the interactions among relevant arguments. The experimental results demonstrate the effectiveness of the proposed method for biomedical event extraction. BioMed Central 2022-07-29 /pmc/articles/PMC9336007/ /pubmed/35906547 http://dx.doi.org/10.1186/s12859-022-04854-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
He, Xinyu
Tai, Ping
Lu, Hongbin
Huang, Xin
Ren, Yonggong
A biomedical event extraction method based on fine-grained and attention mechanism
title A biomedical event extraction method based on fine-grained and attention mechanism
title_full A biomedical event extraction method based on fine-grained and attention mechanism
title_fullStr A biomedical event extraction method based on fine-grained and attention mechanism
title_full_unstemmed A biomedical event extraction method based on fine-grained and attention mechanism
title_short A biomedical event extraction method based on fine-grained and attention mechanism
title_sort biomedical event extraction method based on fine-grained and attention mechanism
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336007/
https://www.ncbi.nlm.nih.gov/pubmed/35906547
http://dx.doi.org/10.1186/s12859-022-04854-0
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