Transforming growth factor-β1 protects against LPC-induced cognitive deficit by attenuating pyroptosis of microglia via NF-κB/ERK1/2 pathways

BACKGROUND: Demyelinating diseases in central nervous system (CNS) are a group of diseases characterized by myelin damage or myelin loss. Transforming growth factor beta1 (TGF-β1) is widely recognized as an anti-inflammatory cytokine, which can be produced by both glial and neuronal cells in CNS. Ho...

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Detalles Bibliográficos
Autores principales: Xie, Yi, Chen, Xuejiao, Li, Ying, Chen, Simiao, Liu, Shuai, Yu, Zhiyuan, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336072/
https://www.ncbi.nlm.nih.gov/pubmed/35902863
http://dx.doi.org/10.1186/s12974-022-02557-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336072/
https://www.ncbi.nlm.nih.gov/pubmed/35902863
http://dx.doi.org/10.1186/s12974-022-02557-0

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