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Blockade of endothelial Mas receptor restores the vasomotor response to phenylephrine in human resistance arterioles pretreated with captopril and exposed to propofol

BACKGROUND: Hypotension that is resistant to phenylephrine is a complication that occurs in anesthetized patients treated with angiotensin converting enzyme (ACE) inhibitors. We tested the hypothesis that Ang 1–7 and the endothelial Mas receptor contribute to vasodilation produced by propofol in the...

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Detalles Bibliográficos
Autores principales: Schulz, Mary E., Hockenberry, Joseph C., Katunaric, Boran, Pagel, Paul S., Freed, Julie K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336100/
https://www.ncbi.nlm.nih.gov/pubmed/35906533
http://dx.doi.org/10.1186/s12871-022-01786-3