CaMKII binds both substrates and activators at the active site

Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is a signaling protein required for long-term memory. When activated by Ca(2+)/CaM, it sustains activity even after the Ca(2+) dissipates. In addition to the well-known autophosphorylation-mediated mechanism, interaction with specific binding pa...

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Detalles Bibliográficos
Autores principales: Özden, Can, Sloutsky, Roman, Mitsugi, Tomohiro, Santos, Nicholas, Agnello, Emily, Gaubitz, Christl, Foster, Joshua, Lapinskas, Emily, Esposito, Edward A., Saneyoshi, Takeo, Kelch, Brian A., Garman, Scott C., Hayashi, Yasunori, Stratton, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336311/
https://www.ncbi.nlm.nih.gov/pubmed/35830796
http://dx.doi.org/10.1016/j.celrep.2022.111064

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