Cargando…
Autopsy in the era of advanced cardiovascular imaging
Historically, autopsy contributed to our current knowledge of cardiovascular anatomy, physiology, and pathology. Major advances in the understanding of cardiovascular diseases, including atherosclerosis and coronary artery disease, congenital heart diseases, and cardiomyopathies, were possible throu...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336584/ https://www.ncbi.nlm.nih.gov/pubmed/35514073 http://dx.doi.org/10.1093/eurheartj/ehac220 |
_version_ | 1784759570469486592 |
---|---|
author | Basso, Cristina Stone, James R |
author_facet | Basso, Cristina Stone, James R |
author_sort | Basso, Cristina |
collection | PubMed |
description | Historically, autopsy contributed to our current knowledge of cardiovascular anatomy, physiology, and pathology. Major advances in the understanding of cardiovascular diseases, including atherosclerosis and coronary artery disease, congenital heart diseases, and cardiomyopathies, were possible through autopsy investigations and clinicopathological correlations. In this review, the importance of performing clinical autopsies in people dying from cardiovascular disease, even in the era of advanced cardiovascular imaging is addressed. Autopsies are most helpful in the setting of sudden unexpected deaths, particularly when advanced cardiovascular imaging has not been performed. In this setting, the autopsy is often the only chance to make the correct diagnosis. In previously symptomatic patients who had undergone advanced cardiovascular imaging, autopsies still play many roles. Post-mortem examinations are important for furthering the understanding of key issues related to the underlying diseases. Autopsy can help to increase the knowledge of the sensitivity and specificity of advanced cardiovascular imaging modalities. Autopsies are particularly important to gain insights into both the natural history of cardiovascular diseases as well as less common presentations and therapeutic complications. Finally, autopsies are a key tool to quickly understand the cardiac pathology of new disorders, as emphasized during the recent coronavirus disease 2019 pandemic. |
format | Online Article Text |
id | pubmed-9336584 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-93365842022-07-29 Autopsy in the era of advanced cardiovascular imaging Basso, Cristina Stone, James R Eur Heart J State of the Art Review Historically, autopsy contributed to our current knowledge of cardiovascular anatomy, physiology, and pathology. Major advances in the understanding of cardiovascular diseases, including atherosclerosis and coronary artery disease, congenital heart diseases, and cardiomyopathies, were possible through autopsy investigations and clinicopathological correlations. In this review, the importance of performing clinical autopsies in people dying from cardiovascular disease, even in the era of advanced cardiovascular imaging is addressed. Autopsies are most helpful in the setting of sudden unexpected deaths, particularly when advanced cardiovascular imaging has not been performed. In this setting, the autopsy is often the only chance to make the correct diagnosis. In previously symptomatic patients who had undergone advanced cardiovascular imaging, autopsies still play many roles. Post-mortem examinations are important for furthering the understanding of key issues related to the underlying diseases. Autopsy can help to increase the knowledge of the sensitivity and specificity of advanced cardiovascular imaging modalities. Autopsies are particularly important to gain insights into both the natural history of cardiovascular diseases as well as less common presentations and therapeutic complications. Finally, autopsies are a key tool to quickly understand the cardiac pathology of new disorders, as emphasized during the recent coronavirus disease 2019 pandemic. Oxford University Press 2022-05-06 /pmc/articles/PMC9336584/ /pubmed/35514073 http://dx.doi.org/10.1093/eurheartj/ehac220 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | State of the Art Review Basso, Cristina Stone, James R Autopsy in the era of advanced cardiovascular imaging |
title | Autopsy in the era of advanced cardiovascular imaging |
title_full | Autopsy in the era of advanced cardiovascular imaging |
title_fullStr | Autopsy in the era of advanced cardiovascular imaging |
title_full_unstemmed | Autopsy in the era of advanced cardiovascular imaging |
title_short | Autopsy in the era of advanced cardiovascular imaging |
title_sort | autopsy in the era of advanced cardiovascular imaging |
topic | State of the Art Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336584/ https://www.ncbi.nlm.nih.gov/pubmed/35514073 http://dx.doi.org/10.1093/eurheartj/ehac220 |
work_keys_str_mv | AT bassocristina autopsyintheeraofadvancedcardiovascularimaging AT stonejamesr autopsyintheeraofadvancedcardiovascularimaging |