Cargando…

PEGylated Recombinant Human Growth Hormone Jintrolong(®) Exhibits Good Long-Term Safety in Cynomolgus Monkeys and Human Pediatric Growth Hormone Deficiency Patients

Jintrolong(®) is a long-acting PEGylated recombinant human growth hormone (PEG-rhGH) developed for weekly injection in patients with pediatric growth hormone deficiency (PGHD). Although PEG modification of therapeutic proteins is generally considered safe, concerns persist about the potential for ad...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Wei, Zhou, Juan, Wu, Chuandong, Zhou, Qian, Li, Xiaoyu, Zhang, Yanlin, Zuo, Conglin, Yin, Jun, Hou, Ling, Wang, Shuyang, Gao, Hongyang, Luo, Tianhong, Jin, Lei, Zhong, Enhong, Wang, Yingwu, Luo, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336684/
https://www.ncbi.nlm.nih.gov/pubmed/35909512
http://dx.doi.org/10.3389/fendo.2022.821588