PEGylated Recombinant Human Growth Hormone Jintrolong(®) Exhibits Good Long-Term Safety in Cynomolgus Monkeys and Human Pediatric Growth Hormone Deficiency Patients

Jintrolong(®) is a long-acting PEGylated recombinant human growth hormone (PEG-rhGH) developed for weekly injection in patients with pediatric growth hormone deficiency (PGHD). Although PEG modification of therapeutic proteins is generally considered safe, concerns persist about the potential for ad...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Zhou, Juan, Wu, Chuandong, Zhou, Qian, Li, Xiaoyu, Zhang, Yanlin, Zuo, Conglin, Yin, Jun, Hou, Ling, Wang, Shuyang, Gao, Hongyang, Luo, Tianhong, Jin, Lei, Zhong, Enhong, Wang, Yingwu, Luo, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9336684/
https://www.ncbi.nlm.nih.gov/pubmed/35909512
http://dx.doi.org/10.3389/fendo.2022.821588

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