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Catalytic enantioselective synthesis of fluoromethylated stereocenters by asymmetric hydrogenation
Fluoromethyl groups possess specific steric and electronic properties and serve as a bioisostere of alcohol, thiol, nitro, and other functional groups, which are important in an assortment of molecular recognition processes. Herein we report a catalytic method for the asymmetric synthesis of a varie...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337738/ https://www.ncbi.nlm.nih.gov/pubmed/35974749 http://dx.doi.org/10.1039/d2sc02685f |