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Catalytic enantioselective synthesis of fluoromethylated stereocenters by asymmetric hydrogenation

Fluoromethyl groups possess specific steric and electronic properties and serve as a bioisostere of alcohol, thiol, nitro, and other functional groups, which are important in an assortment of molecular recognition processes. Herein we report a catalytic method for the asymmetric synthesis of a varie...

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Detalles Bibliográficos
Autores principales:	Yang, Jianping, Ponra, Sudipta, Li, Xingzhen, Peters, Bram B. C., Massaro, Luca, Zhou, Taigang, Andersson, Pher G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337738/ https://www.ncbi.nlm.nih.gov/pubmed/35974749 http://dx.doi.org/10.1039/d2sc02685f

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