Cargando…

Efficient Screening of Coformers for Active Pharmaceutical Ingredient Cocrystallization

[Image: see text] Controlling the physical properties of solid forms for active pharmaceutical ingredients (APIs) through cocrystallization is an important part of drug product development. However, it is difficult to know a priori which coformers will form cocrystals with a given API, and the curre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sugden, Isaac J., Braun, Doris E., Bowskill, David H., Adjiman, Claire S., Pantelides, Constantinos C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337750/ https://www.ncbi.nlm.nih.gov/pubmed/35915670 http://dx.doi.org/10.1021/acs.cgd.2c00433

Ejemplares similares

Accurate and efficient representation of intramolecular energy in ab initio generation of crystal structures. I. Adaptive local approximate models
por: Sugden, Isaac, et al.
Publicado: (2016)

How many more polymorphs of ROY remain undiscovered
por: Beran, Gregory J. O., et al.
Publicado: (2021)

Searching for Suitable Kojic Acid Coformers: From Cocrystals and Salt to Eutectics
por: Sun, Renren, et al.
Publicado: (2023)

Rational Coformer Selection in the Development of 6-Propyl-2-thiouracil Pharmaceutical Cocrystals
por: Acebedo-Martínez, Francisco Javier, et al.
Publicado: (2023)

In silico screening of dicarboxylic acids for cocrystallization with phenylpiperazine derivatives based on both cocrystallization propensity and solubility advantage
por: Cysewski, Piotr
Publicado: (2017)

Computer Aided Design of Solvent Blends for Hybrid Cooling and Antisolvent Crystallization of Active Pharmaceutical Ingredients
por: Watson, Oliver L., et al.
Publicado: (2021)

Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals
por: Wróblewska, Aneta, et al.
Publicado: (2020)

A Review of Coformer Utilization in Multicomponent Crystal Formation
por: Wathoni, Nasrul, et al.
Publicado: (2022)

Efficient Screening for Ternary Molecular Ionic Cocrystals Using a Complementary Mechanosynthesis and Computational Structure Prediction Approach
por: Shunnar, Abeer F., et al.
Publicado: (2020)

A molecularly enhanced proof of concept for targeting cocrystals at molecular scale in continuous pharmaceuticals cocrystallization
por: Asgarpour Khansary, Milad, et al.
Publicado: (2022)

New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties
por: Ma, Panpan, et al.
Publicado: (2023)

Exploring the cocrystallization potential of urea and benzamide
por: Cysewski, Piotr, et al.
Publicado: (2016)

Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization
por: Al-Kazemi, Reham, et al.
Publicado: (2019)

Tuning the Pharmacokinetic Performance of Quercetin by Cocrystallization
por: Haskins, Molly M., et al.
Publicado: (2023)

Differences in Coformer Interactions of the 2,4-Diaminopyrimidines Pyrimethamine and Trimethoprim
por: Alaa Eldin Refat, Lamis, et al.
Publicado: (2022)

Chemical Engineering in the Pharmaceutical Industry, Active Pharmaceutical Ingredients
por: Ende, David
Publicado: (2019)

Competitive cocrystallization and its application in the separation of flavonoids
por: Xia, Yanming, et al.
Publicado: (2021)

Comments on "Dissolution Enhancement of Atorvastatin Calcium by Cocrystallization"
por: Emami, Shahram, et al.
Publicado: (2021)

Cocrystallization of Antifungal Compounds Mediated by Halogen Bonding
por: Benito, Mónica, et al.
Publicado: (2023)

Crystalline Peroxosolvates: Nature of the Coformer, Hydrogen-Bonded Networks and Clusters, Intermolecular Interactions
por: Medvedev, Alexander G., et al.
Publicado: (2020)

Crystal Structure, Solubility, and Pharmacokinetic Study on a Hesperetin Cocrystal with Piperine as Coformer
por: Liu, Yanjie, et al.
Publicado: (2022)

Cocrystals by Design: A Rational Coformer Selection Approach for Tackling the API Problems
por: Singh, Maan, et al.
Publicado: (2023)

Halogen-bonded cocrystallization with phosphorus, arsenic and antimony acceptors
por: Lisac, Katarina, et al.
Publicado: (2019)

Enhanced Dissolution of Naproxen by Combining Cocrystallization and Eutectic Formation
por: Kim, Hakyeong, et al.
Publicado: (2021)

Cocrystallization of ubiquitin–deubiquitinase complexes through disulfide linkage
por: Negron Teron, Kristos I., et al.
Publicado: (2023)

Employing Constant Rate Filtration To Assess Active Pharmaceutical Ingredient Washing Efficiency
por: Shahid, Muhid, et al.
Publicado: (2021)

Low-Frequency Raman Spectroscopy of Pure and Cocrystallized Mycophenolic Acid
por: Wallace, Catherine S., et al.
Publicado: (2023)

Tregitope Peptides: The Active Pharmaceutical Ingredient of IVIG?
por: De Groot, Anne S., et al.
Publicado: (2013)

Structure of the active pharmaceutical ingredient bismuth subsalicylate
por: Svensson Grape, Erik, et al.
Publicado: (2022)

Multicomponent Reactions for the Synthesis of Active Pharmaceutical Ingredients
por: Cores, Ángel, et al.
Publicado: (2022)

An experimental and theoretical charge density study of theophylline and malonic acid cocrystallization
por: Hawkins, Bryson A., et al.
Publicado: (2022)

Supramolecular Sandwiches: Halogen-Bonded Coformers Direct [2+2] Photoreactivity in Two-Component Cocrystals
por: Quentin, Jay, et al.
Publicado: (2020)

Novel Purine Alkaloid Cocrystals with Trimesic and Hemimellitic Acids as Coformers: Synthetic Approach and Supramolecular Analysis
por: Gołdyn, M. R., et al.
Publicado: (2020)

Improving Nefiracetam Dissolution and Solubility Behavior Using a Cocrystallization Approach
por: Buol, Xavier, et al.
Publicado: (2020)

Improving the Solubility, Dissolution, and Bioavailability of Metronidazole via Cocrystallization with Ethyl Gallate
por: Li, Jinhui, et al.
Publicado: (2021)

Structure and absolute configuration of liquid molecules based on adamantane derivative cocrystallization
por: Ou, Guang-Chuan, et al.
Publicado: (2022)

New Cocrystals of Antipsychotic Drug Aripiprazole: Decreasing the Dissolution through Cocrystallization
por: Liu, Wenwen, et al.
Publicado: (2021)

Separation of Etiracetam Enantiomers Using Enantiospecific Cocrystallization with 2-Chloromandelic Acid
por: Nulek, Thitapond, et al.
Publicado: (2022)

Understanding flow chemistry for the production of active pharmaceutical ingredients
por: Burange, Anand S., et al.
Publicado: (2022)

The effects of pH, surfactant, ion concentration, coformer, and molecular arrangement on the solubility behavior of myricetin cocrystals
por: Ren, Shuzhen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_445ils9l7tn284o3rk7cilmmpi