An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis

In this study, we present a unique instance of a patient who developed hemophagocytic lymphohistiocytosis secondary to a triple infection with coronavirus disease 2019 (COVID-19), HIV, and histoplasmosis. We emphasize the proinflammatory dysregulations driving the severity of COVID-19 infection in t...

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Detalles Bibliográficos
Autores principales: Touza, Masara, Mutyala, Monica, Chowdhury, Sudipa, Slim, Jihad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
HIV/AIDS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337782/
https://www.ncbi.nlm.nih.gov/pubmed/35915696
http://dx.doi.org/10.7759/cureus.26428
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author Touza, Masara
Mutyala, Monica
Chowdhury, Sudipa
Slim, Jihad
author_facet Touza, Masara
Mutyala, Monica
Chowdhury, Sudipa
Slim, Jihad
author_sort Touza, Masara
collection PubMed
description In this study, we present a unique instance of a patient who developed hemophagocytic lymphohistiocytosis secondary to a triple infection with coronavirus disease 2019 (COVID-19), HIV, and histoplasmosis. We emphasize the proinflammatory dysregulations driving the severity of COVID-19 infection in this setting and highlight the importance of early diagnosis and targeted therapy of underlying conditions as a method to increase the chance of survival.
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spelling pubmed-93377822022-07-31 An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis Touza, Masara Mutyala, Monica Chowdhury, Sudipa Slim, Jihad Cureus HIV/AIDS In this study, we present a unique instance of a patient who developed hemophagocytic lymphohistiocytosis secondary to a triple infection with coronavirus disease 2019 (COVID-19), HIV, and histoplasmosis. We emphasize the proinflammatory dysregulations driving the severity of COVID-19 infection in this setting and highlight the importance of early diagnosis and targeted therapy of underlying conditions as a method to increase the chance of survival. Cureus 2022-06-29 /pmc/articles/PMC9337782/ /pubmed/35915696 http://dx.doi.org/10.7759/cureus.26428 Text en Copyright © 2022, Touza et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle HIV/AIDS
Touza, Masara
Mutyala, Monica
Chowdhury, Sudipa
Slim, Jihad
An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis
title An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis
title_full An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis
title_fullStr An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis
title_full_unstemmed An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis
title_short An Unusual Case of Secondary Hemophagocytic Lymphohistiocytosis in a Patient Diagnosed With Triple Infection: COVID-19, HIV, and Histoplasmosis
title_sort unusual case of secondary hemophagocytic lymphohistiocytosis in a patient diagnosed with triple infection: covid-19, hiv, and histoplasmosis
topic HIV/AIDS
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337782/
https://www.ncbi.nlm.nih.gov/pubmed/35915696
http://dx.doi.org/10.7759/cureus.26428
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