Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease

Approximately 30% of elderly adults are cognitively unimpaired at time of death despite the presence of Alzheimer’s disease neuropathology at autopsy. Studying individuals who are resilient to the cognitive consequences of Alzheimer’s disease neuropathology may uncover novel therapeutic targets to t...

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Detalles Bibliográficos
Autores principales: Eissman, Jaclyn M, Dumitrescu, Logan, Mahoney, Emily R, Smith, Alexandra N, Mukherjee, Shubhabrata, Lee, Michael L, Scollard, Phoebe, Choi, Seo Eun, Bush, William S, Engelman, Corinne D, Lu, Qiongshi, Fardo, David W, Trittschuh, Emily H, Mez, Jesse, Kaczorowski, Catherine C, Hernandez Saucedo, Hector, Widaman, Keith F, Buckley, Rachel F, Properzi, Michael J, Mormino, Elizabeth C, Yang, Hyun Sik, Harrison, Theresa M, Hedden, Trey, Nho, Kwangsik, Andrews, Shea J, Tommet, Douglas, Hadad, Niran, Sanders, R Elizabeth, Ruderfer, Douglas M, Gifford, Katherine A, Zhong, Xiaoyuan, Raghavan, Neha S, Vardarajan, Badri N, Pericak-Vance, Margaret A, Farrer, Lindsay A, Wang, Li San, Cruchaga, Carlos, Schellenberg, Gerard D, Cox, Nancy J, Haines, Jonathan L, Keene, C Dirk, Saykin, Andrew J, Larson, Eric B, Sperling, Reisa A, Mayeux, Richard, Cuccaro, Michael L, Bennett, David A, Schneider, Julie A, Crane, Paul K, Jefferson, Angela L, Hohman, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337804/
https://www.ncbi.nlm.nih.gov/pubmed/35552371
http://dx.doi.org/10.1093/brain/awac177

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