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A calcium-sensitive antibody isolates soluble amyloid-β aggregates and fibrils from Alzheimer’s disease brain

Aqueously soluble oligomers of amyloid-β peptide may be the principal neurotoxic forms of amyloid-β in Alzheimer’s disease, initiating downstream events that include tau hyperphosphorylation, neuritic/synaptic injury, microgliosis and neuron loss. Synthetic oligomeric amyloid-β has been studied exte...

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Detalles Bibliográficos
Autores principales:	Stern, Andrew M, Liu, Lei, Jin, Shanxue, Liu, Wen, Meunier, Angela L, Ericsson, Maria, Miller, Michael B, Batson, Megan, Sun, Tingwan, Kathuria, Sagar, Reczek, David, Pradier, Laurent, Selkoe, Dennis J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337809/ https://www.ncbi.nlm.nih.gov/pubmed/35084489 http://dx.doi.org/10.1093/brain/awac023

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