Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer’s disease

Microtubules play fundamental roles in the maintenance of neuronal processes and in synaptic function and plasticity. While dynamic microtubules are mainly composed of tyrosinated tubulin, long-lived microtubules contain detyrosinated tubulin, suggesting that the tubulin tyrosination/detyrosination...

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Detalles Bibliográficos
Autores principales: Peris, Leticia, Parato, Julie, Qu, Xiaoyi, Soleilhac, Jean Marc, Lanté, Fabien, Kumar, Atul, Pero, Maria Elena, Martínez-Hernández, José, Corrao, Charlotte, Falivelli, Giulia, Payet, Floriane, Gory-Fauré, Sylvie, Bosc, Christophe, Blanca Ramirez, Marian, Sproul, Andrew, Brocard, Jacques, Di Cara, Benjamin, Delagrange, Philippe, Buisson, Alain, Goldberg, Yves, Moutin, Marie Jo, Bartolini, Francesca, Andrieux, Annie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337816/
https://www.ncbi.nlm.nih.gov/pubmed/35148384
http://dx.doi.org/10.1093/brain/awab436

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