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Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency

A prophylactic hepatitis C virus (HCV) vaccine that elicits neutralizing antibodies could be key to HCV eradication. However, the genetic and antigenic properties of HCV envelope (E1E2) proteins capable of inducing anti-HCV broadly neutralizing antibodies (bNAbs) in humans have not been defined. Her...

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Detalles Bibliográficos
Autores principales:	Frumento, Nicole, Figueroa, Alexis, Wang, Tingchang, Zahid, Muhammad N., Wang, Shuyi, Massaccesi, Guido, Stavrakis, Georgia, Crowe, James E., Flyak, Andrew I., Ji, Hongkai, Ray, Stuart C., Shaw, George M., Cox, Andrea L., Bailey, Justin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337827/ https://www.ncbi.nlm.nih.gov/pubmed/35588376 http://dx.doi.org/10.1172/JCI160058

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