Upregulation of NKG2D ligands impairs hematopoietic stem cell function in Fanconi anemia

Fanconi anemia (FA) is the most prevalent inherited bone marrow failure (BMF) syndrome. Nevertheless, the pathophysiological mechanisms of BMF in FA have not been fully elucidated. Since FA cells are defective in DNA repair, we hypothesized that FA hematopoietic stem and progenitor cells (HSPCs) mig...

Descripción completa

Detalles Bibliográficos
Autores principales: Casado, José A., Valeri, Antonio, Sanchez-Domínguez, Rebeca, Vela, Paula, López, Andrea, Navarro, Susana, Alberquilla, Omaira, Hanenberg, Helmut, Pujol, Roser, Segovia, José-Carlos, Minguillón, Jordi, Surrallés, Jordi, de Heredia, Cristina Díaz, Sevilla, Julián, Rio, Paula, Bueren, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337828/
https://www.ncbi.nlm.nih.gov/pubmed/35671096
http://dx.doi.org/10.1172/JCI142842

Ejemplares similares

Ejemplares similares