Neuroprotection against ischemic stroke requires a specific class of early responder T cells in mice

Immunomodulation holds therapeutic promise against brain injuries, but leveraging this approach requires a precise understanding of mechanisms. We report that CD8(+)CD122(+)CD49d(lo) T regulatory-like cells (CD8(+) TRLs) are among the earliest lymphocytes to infiltrate mouse brains after ischemic st...

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Detalles Bibliográficos
Autores principales: Cai, Wei, Shi, Ligen, Zhao, Jingyan, Xu, Fei, Dufort, Connor, Ye, Qing, Yang, Tuo, Dai, Xuejiao, Lyu, Junxuan, Jin, Chenghao, Pu, Hongjian, Yu, Fang, Hassan, Sulaiman, Sun, Zeyu, Zhang, Wenting, Hitchens, T. Kevin, Shi, Yejie, Thomson, Angus W., Leak, Rehana K., Hu, Xiaoming, Chen, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337834/
https://www.ncbi.nlm.nih.gov/pubmed/35912857
http://dx.doi.org/10.1172/JCI157678

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