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TOP2A correlates with poor prognosis and affects radioresistance of medulloblastoma

Radiotherapy remains the standard treatment for medulloblastoma (MB), and the radioresistance contributes to tumor recurrence and poor clinical outcomes. Nuclear DNA topoisomerase II-alpha (TOP2A) is a key catalytic enzyme that initiates DNA replication, and studies have shown that TOP2A is closely...

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Detalles Bibliográficos
Autores principales:	Zhang, Yufeng, Yang, Haiyan, Wang, Liwen, Zhou, Huandi, Zhang, Ge, Xiao, Zhiqing, Xue, Xiaoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337862/ https://www.ncbi.nlm.nih.gov/pubmed/35912241 http://dx.doi.org/10.3389/fonc.2022.918959

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