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YAP1 induces invadopodia formation by transcriptionally activating TIAM1 through enhancer in breast cancer
Yes-associated protein 1 (YAP1), a central component of the Hippo pathway, plays an important role in tumor metastasis; however, the underlying mechanism remains to be elucidated. Invadopodia are actin-rich protrusions containing multiple proteases and have been widely reported to promote cell invas...
Autores principales: | Shen, Jie, Huang, Qingwen, Jia, Weiyi, Feng, Shengjie, Liu, Liang, Li, Xiaolan, Tao, Deding, Xie, Daxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337990/ https://www.ncbi.nlm.nih.gov/pubmed/35773411 http://dx.doi.org/10.1038/s41388-022-02344-4 |
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