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YAP1 induces invadopodia formation by transcriptionally activating TIAM1 through enhancer in breast cancer

Yes-associated protein 1 (YAP1), a central component of the Hippo pathway, plays an important role in tumor metastasis; however, the underlying mechanism remains to be elucidated. Invadopodia are actin-rich protrusions containing multiple proteases and have been widely reported to promote cell invas...

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Detalles Bibliográficos
Autores principales: Shen, Jie, Huang, Qingwen, Jia, Weiyi, Feng, Shengjie, Liu, Liang, Li, Xiaolan, Tao, Deding, Xie, Daxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9337990/
https://www.ncbi.nlm.nih.gov/pubmed/35773411
http://dx.doi.org/10.1038/s41388-022-02344-4

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