Stochastic models of Mendelian and reverse transcriptional inheritance in state-structured cancer populations

Recent evidence suggests that a polyaneuploid cancer cell (PACC) state may play a key role in the adaptation of cancer cells to stressful environments and in promoting therapeutic resistance. The PACC state allows cancer cells to pause cell division and to avoid DNA damage and programmed cell death....

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Detalles Bibliográficos
Autores principales: Bukkuri, Anuraag, Pienta, Kenneth J., Austin, Robert H., Hammarlund, Emma U., Amend, Sarah R., Brown, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338039/
https://www.ncbi.nlm.nih.gov/pubmed/35906318
http://dx.doi.org/10.1038/s41598-022-17456-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338039/
https://www.ncbi.nlm.nih.gov/pubmed/35906318
http://dx.doi.org/10.1038/s41598-022-17456-w

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