An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis

Lipid remodeling is crucial for malignant cell transformation and tumorigenesis, but the precise molecular processes involved and direct evidences for these in vivo remain elusive. Here, we report that oxysterol-binding protein (OSBP)-related protein 4 L (ORP4L) is expressed in adult T-cell leukemia...

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Detalles Bibliográficos
Autores principales: Zhong, Wenbin, Lin, Weize, Yang, Yingjie, Chen, Dan, Cao, Xiuye, Xu, Mengyang, Pan, Guoping, Chen, Huanzhao, Zheng, Jie, Feng, Xiaoqin, Yang, Li hua, Lai, Chaofeng, Olkkonen, Vesa M., Xu, Jun, Cui, Shuzhong, Yan, Daoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338045/
https://www.ncbi.nlm.nih.gov/pubmed/35906240
http://dx.doi.org/10.1038/s41467-022-32104-7

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