Safety, Tolerability, Pharmacokinetics and Initial Pharmacodynamics of a Subcommissural Organ-Spondin-Derived Peptide: A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose First-in-Human Study

INTRODUCTION: This randomized, double-blind, placebo-controlled study in healthy volunteers assessed the safety, tolerability, and pharmacokinetics of single ascending doses of intravenously administered NX210—a linear peptide derived from subcommissural organ-spondin—and explored the effects on blo...

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Detalles Bibliográficos
Autores principales: Bourdès, Valérie, Dogterom, Peter, Aleman, André, Parmantier, Pierre, Colas, Damien, Lemarchant, Sighild, Marie, Sébastien, Chou, Thomas, Abd-Elaziz, Khalid, Godfrin, Yann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9338184/
https://www.ncbi.nlm.nih.gov/pubmed/35779189
http://dx.doi.org/10.1007/s40120-022-00380-6

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